Crystal structure of human Haspin (GSG2) kinase bound to chemical probe MU1920
收藏Protein Data Bank Japan2025-03-26 更新2026-04-19 收录
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Crystal structure of human Haspin (GSG2) kinase bound to chemical probe MU1920 Descriptor: NICKEL (II) ION, Serine/threonine-protein kinase haspin, ~{N}-(1,4-dimethylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridin-5-amine Authors: Kraemer, A, Paruch, K, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2024-06-05 Release date: 2024-09-11 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Thieno[3,2-b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode. Angew.Chem.Int.Ed.Engl., 64, 2025
创建时间：
2024-06-05
