Chan-Soo Lee, Chang-Ki Choi, Eun-Young Shin, Martin Alexander Schwartz, Eung-Gook Kim (2011) CIL:26539, Mus musculus, fibroblast. CIL. Dataset

To study the molecular mechanism by which nonmuscle myosin II (MII) regulates protrusion and adhesion dynamics in migrating cells, Swiss3T3 cells were transfected with a plasmid encoding myc-tagged βPIX (green, stained for myc-βPIX) and costained myosin IIA (red). These findings help elucidate a functional link between MII and Rac1/Cdc42 GTPases, which may regulate protrusion/adhesion dynamics in migrating cells. This image is the original data file from Fig. S1, J. Cell Biol. 2010. Vol. 190(4):663–674

为探究非肌肉肌球蛋白II（MII）调控迁移细胞突起和粘附动态的分子机制，研究人员将编码myc标记βPIX（绿色，用于myc-βPIX染色）的质粒转染至Swiss3T3细胞中，并与肌球蛋白IIA（红色）进行共染色。这些研究结果有助于阐明MII与Rac1/Cdc42 GTP酶之间的功能联系，这些酶可能调节迁移细胞中的突起/粘附动态。此图像为图S1的原始数据文件，来源于《细胞生物学杂志》2010年第190卷第4期，第663-674页。