Cryo-EM structure of human XPR1 in complex with InsP8

Cryo-EM structure of human XPR1 in complex with InsP8 Descriptor: (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], Solute carrier family 53 member 1 Authors: Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. Deposit date: 2024-10-11 Release date: 2025-08-27 Last modified: 2025-09-17 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1. Mol.Cell, 85, 2025