Whole genome sequencing data of TK6 human lymphoblastoid cell line

To improve the accuracy and cost-efficiency of the consensus sequencing strategy, we developed a PCR-free duplex consensus sequencing approach, termed the Paired-End and Complementary Consensus Sequencing (PECC-Seq). PECC-Seq employed shear points as endogenous barcodes to identify consensus sequences from the overlap in the shortened, complementary DNA strands-derived paired-end reads for sequencing error correction. We then applied PECC-Seq to TK6 human lymphoblastoid cell line to detect the chemical-induced low-frequency mutations.