Expression data from wild type and Sox17 heterozygous mutant uteri in early pregnancy

SOX17 activity in the uterine epithelium is essential for the implantation of mouse embryos. Previously, we demonstrated that female Sox17-heterozygous mutant mice are subfertile, and two active copies of Sox17 are required for the proper implantation of mouse embryos. To understand which implantation step is most sensitive to the Sox17 gene dosage, we comprehensively investigated the RNA transcriptomes of Sox17-heterozygous mutant mice. Total RNA prepared from the uterine epithelium of wild-type and Sox17GFP/+ female mice was used for microarray analysis with a GeneChip® 3' IVT PLUS Reagent Kit (Affymetrix, CA, USA)