Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10
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Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10 Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10 Authors: Song, X, Wang, M, Yang, N, Xu, R.M. Deposit date: 2019-03-13 Release date: 2019-09-18 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3.6 Å) Cite: A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity. Proc.Natl.Acad.Sci.USA, 116, 2019
创建时间:
2019-03-13



