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DENN-4, the putative RAB-10 GEF, is required for dendritic morphogenesis in PVD.

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Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_DENN_4_the_putative_RAB_10_GEF_is_required_for_dendritic_morphogenesis_in_PVD_/1618351
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(A) Schematic of somatic CRISPR targeting construct used to produce conditional denn-4 mutations. (B) Representative image of PVD::GFP in a heat-shocked WT control animal. (C) Representative image of PVD::GFP in the conditional denn-4 CRISPR allele. (D) Efficiency of conditional CRISPR denn-4 knockout in generating PVD-phenotype in all conditions and genotypes tested. (E) Quantification of subcellular distribution of branch complexity in this allele. Scale bars represent 20 μm. Error bars represent SEM. * p
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2016-02-23
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