Hepcidin Inhibits Hepatocyte Apoptosis via the PERK Pathway in Acute Liver Injury and Fibrosis. Hepcidin Inhibits Hepatocyte Apoptosis via the PERK Pathway in Acute Liver Injury and Fibrosis

RNA transcription profiling of hepatocytes was compared between C57BL/6 mice and Hamp-/- mice for 24h Overall design: Four-week-old male WT and Hamp-/- mice were randomly divided into the CCl4 and vehicle groups (n=6). The mice were administered 12.5% CCl4 (CCl4: olive oil= 1:7) or vehicle (olive oil) for 24 h.