ND1 ex vivo gene therapy modulates the transcription of genes relevant to AD pathogenesis
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE149599
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资源简介：
Transcriptome analysis of human iPSC-derived hippocampal neurons overexpresing NEUROD1 We employed Affymetrix GeneChip microarray (Human Clariom D) to examine early transcriptomic changes in APP variant cells compared to control, upon viral delivery of ND1. Human iPSC-derived hippocampal neurons from healthy donor and Alzheimer's disease patient carrying APP mutation were transfected with GFP or NEUROD1. Three biological replicates were performed. Summarized probe set signals in log2 scale were calculated by using the GCCN-SST-RMA algorithm with the Affymetrix GeneChip Expression Console v1.4 Software.
创建时间：
2020-07-30
