A conserved linker between fingers 2 and 3 of KLFs is requried for full in vivo DNA binding affinity, phosphorylation and function
收藏Alliance of Genome Resources2026-08-01 收录
官方服务：
资源简介：
A disease causing linker mutation in KLF1 alters in vivo DNA binding affinity RNAseq and ChIPseq in 14.5DPC fetal livers --------------------------------- The comparisons in cuffdiff corresponds as follows: Q1 KLF1 D45/- mRNAseq Q2 KLF1 -/- mRNAseq Q3 KLF1 +/- mRNAseq
Krüppel样因子1（KLF1）中的致病接头突变可改变14.5天交配后天（14.5DPC）胎肝中的体内DNA结合亲和力，并影响其RNA测序（RNAseq）与染色质免疫沉淀测序（ChIPseq）数据—— 采用Cuffdiff进行的各组比较对应如下：Q1组为KLF1 D45/- 信使RNA测序（mRNAseq）样本，Q2组为KLF1 -/- 信使RNA测序样本，Q3组为KLF1 +/- 信使RNA测序样本
