Mutation analysis of human RHOX genes. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA329175
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资源简介：
The X-linked reproductive homeobox (RHOX) gene cluster encodes transcription factors displaying preferential expression in reproductive tissues. They have important roles in human male fertility based on phenotypic defects of Rhox-mutant mice and the finding that aberrant RHOX promoter methylation is strongly associated with abnormal human sperm parameters. We hypothesized that the RHOX cluster is involved in the regulation of genes important for spermatogenesis and that alterations to RHOX genes might be associated with idiopathic male infertility. Therefore, we sequence the entire coding region of the RHOX genes in patients with severe oligozoospermia.
创建时间：
2016-07-15
