Welfare-related assessments.
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a Applied for non-invasive procedures (electrocardiogram, bioluminescence imaging) or for terminal bleeding.
b Includes 3 days to acclimation before study star/ and statement to follow 3R's principle.
c Includes anticipated end points in parasitaemia peak or with severe adverse effects, refined oral administration or oral volume up to 50 μL/animal or 7 to 10 days to acclimation before study starts.
d Methods: tribromoethanol followed by decapitation; dyethyl-ether followed by cervical dislocation; thiopental overdose; CO2 inhalation.
e CO2 inhalation in all cases.
Welfare-related assessments.
创建时间:
2015-11-20



