OCTET Statistical Analysis Plan

<b>Scientific title</b> Obsessive Compulsive Treatment Efficacy Trial (OCTET) <b>Acronym</b> OCTET<b>ISRCTN Registration</b>ISRCTN73535163 DOI 10.1186/ISRCTN73535163 <b>Study hypothesis</b> 1. Identify and confirm estimated recruitment rates for an obsessive compulsive disorder (OCD) treatment trial via an internal pilot phase aimed at evaluating recruitment rates and primary outcome point<br> 2. Proceed seamlessly to a full RCT (if recruitment is successful in the pilot phase) to determine:<br> 2.1. The clinical and cost-effectiveness of two self-managed CBT interventions (cCBT and bibliotherapy) compared to a CBT waiting list in the management of OCD patients in the short term at 3- and 6-month follow-up<br> 2.2. The clinical and cost-effectiveness of self-managed therapies plus conventional CBT compared to waiting list plus conventional CBT at 12-month follow-up <br> 3. Determine patient compliance and patient and health professional acceptability of the two self-managed therapy packages (cCBT &amp; GSH)<br> <br> More details can be found at http://www.nets.nihr.ac.uk/projects/hta/098101<br> Protocol can be found at http://www.nets.nihr.ac.uk/__data/assets/pdf_file/0006/54699/PRO-09-81-01.pd