Comparison of the Damaged Cartilage with the Non-weight Bearing Healthy Cartilage

The cartilage samples from patient with Internatinaol Cartilage Repair Society's Scoring 3-4 cartilage defects were analysed in order to understand the differences between healthy and damaged cartilage tissues from the knee. Differential Expression profiling by array. Total RNA was isolated from samples collected from patients during the surgery with RNeasy Mini kit. Affymetrix Primeview human Expression kit chips were used following to affimetrix IVT kit. The data analysed with expression console and Trancriptome Analysis Console.