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Test No. 476: In vitro Mammalian Cell Gene Mutation Test

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Organisation for Economic Co-operation and Development2026-04-11 收录
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https://www.oecd.org/en/publications/test-no-476-in-vitro-mammalian-cell-gene-mutation-test_9789264071322-en.html
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The in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances. In the cell lines the most commonly-used genetic endpoints measure mutation at thymidine kinase (TK) and hypoxanthine-guanine ...
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