Systematic overview of neuroanatomical differences in ADHD: Definitive evidence

<b>Objectives</b>: This article seeks to identify neuroanatomical differences in ADHD through an overview of systematic reviews that report encephalic differences compared to a control group in volume, area, activation likelihood or chemical composition. <b>Methods</b>: We conducted a systematic search using Cochrane guidelines and PRISMA criteria in PubMed, Scopus, Web of Science, Cochrane Database of Systematic Reviews and Database of Abstracts of Reviews of Effects. <b>Results</b>: Results revealed broad encephalic involvement that includes a functional frontal and cingulate hypoactivation and structural differences in corpus callosum, cerebellum and basal nuclei. <b>Conclusions</b>: ADHD symptoms might be due to a multi-network unbalanced functioning hypothesis.