Different expression profiles of lncRNA, mRNA and circRNA in peripheral blood (ceRNA) of normal newborns and children with BPD.. Different expression profiles of lncRNA, mRNA and circRNA in peripheral blood (ceRNA) of normal newborns and children with BPD.

Increasing evidence shows that circular RNAs (circRNAs) play a vital role in the development of various diseases. A recent sequencing analysis of peripheral blood of bronchopulmonary dysplasia (BPD) patients showed that circABCC4 expression was significantly up-regulated. However, the specific function and potential mechanism of circRNAs in BPD remain unclear. Overall design: Two peripheral blood samples of a normal newborn and a premature infant with BPD were included. There are no duplicate samples, control samples and/or reference samples or pigment exchanges.