Neural activity recorded in breast tumors originates from the sympathetic nervous

The autonomic nervous system (ANS) is a regulator of major pathological events in the tumor microenvironment (TME) of solid carcinomas where the branches of ANS have antagonistic effects on tumor growth and metastasis. Neural activity recorded from breast tumors may be associated with autonomic system function. We perform RNA sequencing to analyze the transcriptomic change in the onset of neural activity.