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Data underlying the publication: "Unraveling the TRAPP Complex in Toxoplasma gondii: Its Role in Endocytic Vesicle Trafficking"

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4TU.ResearchData2025-06-02 更新2026-04-23 收录
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https://data.4tu.nl/datasets/b49e2329-a90a-4724-8a4c-9510ffffb0bb/1
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资源简介:
This dataset contains the raw data underlying the figures in the study <em>'Unraveling the TRAPP Complex in Toxoplasma gondii: Its Role in Endocytic Vesicle Trafficking,'</em> which investigates the molecular mechanisms of vesicle trafficking in <em>T. gondii</em>. The data include proteomic Dataset from Bet3 co-immunoprecipitation (Co-IP), raw colocalization measurements obtained using a Nikon Ni-E automated microscope and analyzed with NIS Elements AR software, plaque assay counts and areas, parasite invasion/proliferation/egress quantifications, gliding motility distances, GFP trafficking population counts, biotin uptake assay immunoblot band intensities, and TEM-based measurements of parasitophorous vacuole (PV) areas. These datasets support the statistical analyses and graphical representations in the associated publication.

本数据集包含发表于论文《解析刚地弓形虫TRAPP复合物:其在内吞囊泡转运中的功能》的所有配图的原始实验数据。该研究旨在阐明刚地弓形虫的囊泡转运分子机制。本数据集涵盖Bet3蛋白免疫共沉淀(Co-IP)蛋白质组数据集、采用尼康Ni-E全自动显微镜采集并经NIS Elements AR软件分析的共定位原始定量数据、噬斑实验的计数与面积数据、寄生虫入侵、增殖与逸出定量数据、滑行运动距离数据、GFP标记的囊泡转运种群计数数据、生物素摄取实验的免疫印迹条带灰度值数据,以及基于透射电子显微镜(Transmission Electron Microscope, TEM)的纳虫空泡(PV)面积测量数据。本数据集为该关联发表论文中的统计分析与图形展示提供了完整的数据支撑。
提供机构:
Tang, Tao; Ying, Zhu; Liu, Jing; Tang, Yi-Dan; Liu, Qun; Long, Shaojun
创建时间:
2025-06-02
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