Gene expression in ACSL5-wildtype and ACSL5-deficient LM3 cells with PA treatment

Metastasis accounts for 90% of cancer-related death. Distant metastasis follows a non-random pattern, termed “organotropism”. The lung is a common site for BC metastasis, yet the underlying mechanisms and treatment strategies for lung metastasis remain unclear. Overall design: To investigate the role of ACSL5 mediate lung-tropic metastasis of breast tumors, we performed high-throughput sequencing in ACSL5-wildtype and ACSL5-deficient LM3 cells treated with or without PA.