Trabecular meshwork cell-derived exosomal microRNA expression

Trabecular meshwork cells in eyes with glaucoma aquire mesenchymal phenotypes. The types of microRNAs in exosomes may differ between static and glaucomatous status and their effects on aqueous humor regulation are still uknown. We used microarrays to identify the differential microRNA expression related to interaction between trabecular meshwork cells and Schlemm's canal endothelial cells. Transcriptomic profile of microRNAs in exosomes derived from monkey trabecular meshwork cells treated with TGF-β2, collagen type 1 or those without (controls).