Berkeleydione and Berkeleytrione, New Bioactive Metabolites from an Acid Mine Organism
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https://figshare.com/articles/dataset/Berkeleydione_and_Berkeleytrione_New_Bioactive_Metabolites_from_an_Acid_Mine_Organism/3346138
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资源简介：
Two novel hybrid polyketide-terpenoid metabolites were isolated from a Penicillium sp. growing in the Berkeley Pit Lake of Butte, Montana.
Their structures were deduced by spectroscopic analysis and confirmed by single-crystal X-ray analysis on berkeleydione (1). Both compounds
inhibited matrix metalloproteinase-3 and caspase-1, and berkeleydione showed activity toward non-small-cell lung cancer in NCI's human cell
line antitumor screen.
创建时间：
2004-03-18
