Effect of small molecules on activated BV2 microglia cell line. Mus musculus
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We have developed an assay to test the neuroprotective properties of compounds using stem cell–derived motor neurons and astrocytes, together with activated microglia as a stress paradigm. Hit compounds were discovered and the transcriptional response on activated BV2 cells was tested. Overall design: The BV2 cell line was activated with LPS and IFN-γ and treated with hit compound for 4 hr.
创建时间:
2012-04-26



