Base case results.*

*The table presents undiscounted HIV infections averted, and discounted QALYs and costs (discounted to the present at 3% annually). IDU = injection drug user; PrEP = oral pre-exposure prophylaxis for injection drug users; ART = antiretroviral therapy for 80% of eligible individuals; MMT = methadone maintenance treatment for 25% of IDUs; 25% PrEP = PrEP for 25% of uninfected IDUs; 50% PrEP = PrEP for 50% of uninfected IDUs.**The numbers for similar strategies vary because of dynamics. For example, for the strategy “25% PrEP,” 13,686 IDUs receive PrEP, whereas for the strategy “ART, 25% PrEP,” 14,506 IDUs receive PrEP; this is because with scaled up ART, IDUs live longer, so 25% of IDUs on PrEP with ART scale up is greater than 25% of IDUs on PrEP without ART scale up.***Incremental to the status quo.