Human NLRP3 complex with compound 2 in the closed hexamer
收藏Protein Data Bank Japan2025-03-12 更新2026-04-19 收录
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https://pdbj.org/mine/summary/9mie
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Human NLRP3 complex with compound 2 in the closed hexamer Descriptor: (2P)-2-(4-{[(3R)-1-methylpiperidin-3-yl]amino}-6,7-dihydro-5H-cyclopenta[d]pyridazin-1-yl)-5-(trifluoromethyl)phenol, ADENOSINE-5'-TRIPHOSPHATE, NACHT, ... Authors: Mammoliti, O, Carbajo, R.J, Perez-Benito, L, Yu, X. Deposit date: 2024-12-12 Release date: 2025-02-26 Last modified: 2025-03-12 Method: ELECTRON MICROSCOPY (3.93 Å) Cite: Discovery of Potent and Brain-Penetrant Bicyclic NLRP3 Inhibitors with Peripheral and Central In Vivo Activity. J.Med.Chem., 68, 2025
创建时间：
2024-12-12
