Crystal structure of EHMT2 SET domain in complex with compound 10
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Crystal structure of EHMT2 SET domain in complex with compound 10 Descriptor: 5'-methoxy-6'-(1-methyl-2,3,4,7-tetrahydroazepin-5-yl)spiro[cyclobutane-1,3'-indole]-2'-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ... Authors: Suzuki, M, Katayama, K. Deposit date: 2020-10-26 Release date: 2021-02-10 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of DS79932728: A Potent, Orally Available G9a/GLP Inhibitor for Treating beta-Thalassemia and Sickle Cell Disease. Acs Med.Chem.Lett., 12, 2021
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2020-10-26
