Metabolites that differed significantly between control and UQ groups at 2-y follow-up (p<0.05).

Metabolites have been classified into structural or functional classes. Within each class, data have been separated into those with higher (where such exist) and lower ratios, respectively, and are then presented in order from lowest to highest p value. The molecular weights, calculated as the monoisotopic mass, are included. Ratios with 95% confidence intervals in parentheses are shown. DM, demethyl, G, glycine; P, proline; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PG, glycerophosphoglycerol; PS, phosphatidylserine; R, arginine; V, valine; The values in parentheses (for example PC(34∶0)) relate to the total fatty acid carbon chain length and number of carbon double bonds (unsaturation) in each metabolite. *Identification by matching of retention time and accurate mass to authentic chemical standardMetabolites that differed significantly between control and UQ groups at 2-y follow-up (p