USP1 identified as an important factor in the progression of gastric cancer

Gastric cancer is one of the leading causes of cancer-related deaths, and through in vivo and in vitro genetic screens, we identified USP1 as an important factor in promoting tumor progression. Here, we analyzed the transcriptome of sh-USP after knockdown with the aim of identifying downstream effectors of USP1 Overall design: RNA-seq analysis of human gastric cancer cell line AGS using shCtrl or shUSP1