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Transcriptome analyses of PROKR1-activated HEK293T cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE148443
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In order to gain insight into the molecular mechanism of PROKR1, we investigated transcriptomic response in PROKR1 overexpressed HEK293 T cells following Pk2 stimulation We identified 578 differentially expressed genes (DEGs) fold change cutoff = 2 in activated HEK293 T overexpressed HEK293 T cells by Pk2, including 269 up-regulated and 309 down-regulated genes. These results indicate that MAPK / Erk and PI3K / Akt signaling pathways are putative signaling pathways that are dominantly affected by Prokr1 activation.
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2025-08-06
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