During development, nephron progenitor forming one million nephrons, a functional unit in the kidney. However, nephron progenitor ceases before birth in human when they terminally differentiated to th

干细胞与再生医学数据中心2022-02-20 更新50

Neonatal nephron loss during active nephrogenesis results in altered expression of renal developmental genes and markers of kidney injury

肾脏发育

肾脏损伤

Preterm neonates are at high risk for nephron loss under adverse clinical conditions (e.g., cardiocirculatory decompensation, nephrotoxic drugs). Importantly, the onset of renal damage potentially col

干细胞与再生医学数据中心2022-02-20 更新90

Supplementary Material for: Prioritization of monogenic CAKUT candidate genes with existing single-cell transcriptomics data of the human fetal kidney

基因表达分析

肾脏发育

Introduction: Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of chronic kidney disease in the first three decades of life. Over 40 genes have been identified as

DataCite Commons2023-10-14 更新60

10.5dpc Metanephric mesenchyme Vs 13.5dpc fetal kidney

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