Supplementary Material for: Hypoalbuminemia and generalized edema as the presenting symptoms of celiac disease in a two-year-old girl – case report

Celiac disease is a systemic, immune-mediated enteropathy that occurs following dietary consumption of gluten in genetically susceptible individuals. The global prevalence of celiac disease is estimated to be approximately 1.4%, with variation based on age, sex, and geographic location. Celiac disease typically presents early in life with diarrhea, abdominal pain, abdominal distention, weight loss, and impaired growth. In severe cases, patients with celiac disease can present in a state of celiac crisis, classically characterized with profuse diarrhea and life-threatening metabolic derangements. In this report, we discuss a 23-month-old girl who presented atypically with hypoalbuminemia and generalized edema.