Integrative Multi-omics Analysis Reveals Candidate Biomarkers for Oral Squamous Cell Carcinoma
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP343653
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资源简介：
We analyzed differentially expressed genes (DEGs) associated with OSCC using RNA sequencing technology. Methylation-regulated and differentially expressed genes (MeDEGs) of OSCC were further identified via an integrative approach by examining methylomic datasets together with our own transcriptomic data. Protein-protein interaction (PPI) networks of MeDEGs were constructed and highly connected hub MeDEGs were identified from these PPI networks. A total of 56 upregulated MeDEGs and 170 downregulated MeDEGs were identified in OSCC. Eleven hub genes with high degree of connectivity were picked out from the protein-protein interaction (PPI) networks constructed by those MeDEGs. Overall design: RNA profiles of 17 paired samples of OSCC and NAT
创建时间：
2023-11-14
