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Expression data from RCC cell lines to study metastasis progression

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE23627
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This study investigates the molecular signatures that drive Renal Cell Carcinoma (RCC) metastatic conversion using the metastatic (LM2) and non-metastatic (SN12C) RCC cell lines. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process. To identify differences in gene expression associated with increasing metastatic activity, we subjected the three RCC cell types, SN12C, LM1, LM2 to gene expression profiling.
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2019-03-25
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