Source Data Figure 3 .xlsx

b, d, the corresponding Osteoarthritis Research Society International
(OARSI) scores from normal, sham, veh (vehicle)-treated, and BNTA-treated rats at
4 w and 8 w (n = 8 for each group; nonparametric test). e, Pain response times when
rats were placed on the 55 °C hot plate meter at 4 w and 8 w post-surgery (n =
8 for each group, one-way ANOVA).
f, The difference between the weight placed on the contralateral sham
(left) hindlimb and the weight placed on the anterior cruciate ligament
transection (ACLT, right) one at 4 w
and 8 w post-surgery (n = 8 for each group, one-way ANOVA). Each data point represents
one individual rat. All data are shown as the mean ± standard deviation (s. d.).
*P < 0.05, **P < 0.01, ***P <
0.001.