Lympho-myeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells

An immune-restricted lymphomyeloid-primed progenitor with the capacity to contribute to both myeloid and lymphoid lineages in the developing embryo emerges prior to definitive HSCs. Examination of fetal sorted lymphoid primed progenitors and adult progenitors The fastq files are not provided at this time due to further analyses.在定型造血干细胞（definitive hematopoietic stem cells，HSCs）出现之前，发育中的胚胎内便已产生一种免疫受限的淋巴髓系定向祖细胞（immune-restricted lymphomyeloid-primed progenitor），该细胞兼具向髓系与淋巴系谱系分化的潜能。对胎儿分选得到的淋巴系定向祖细胞（lymphoid primed progenitors）及成体祖细胞的检测研究。鉴于当前正开展进一步分析，暂未提供fastq文件。