CDKN2A–EGFR–TERT Pathway Subtype Network

Pathways characterizing CDKN2A–EGFR–TERT subtypes, defined as subnetwork regions extracted from ReactomeFI by NBS. (Fig. 5e)Red circles indicate gain of function.Blue circles indicate loss of function.Yellow nodes indicate noncoding mutations.Cyan nodes indicate coding alteration.Blue arrows indicate protein-protein activation.Blue lines indicate protein-protein inhibition.Pink lines indicate complex protein-protein interaction.Grey lines indicate protein binding from high-throughput experiments.Red arrows indicate transcriptional activation.Red lines indicate transcriptional repression.Green lines indicate genetic interaction.