Distribution of ApoE<sup>null</sup> mice oral microbial samples positive for bacterial genomic DNA by PCR.
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aIndicate time points at which oral microbial samples were collected (2, 8, 14, and 16 weeks) following polymicrobial infection for determination of microbial colonization by species specific PCR analysis. bIndicate mice were infected for 8 alternate weeks with P. gingivalis, T. denticola, and T. forsythia. Samples were analyzed using appropriate specific PCR primers with positive and negative controls. cOral microbial samples were collected from sham-infected control mice periodically and examined for P. gingivalis, T. denticola, and T. forsythia using bacteria specific primers and all mice were negative. - Indicate oral microbial samples negative by PCR analysis. Pg-indicate P. gingivalis; Td-indicate T. denticola; and Tf-indicate T. forsythia.
