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Crystal Structure of Human cystathionine beta-synthase variant R336C

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Protein Data Bank Japan2025-10-01 更新2026-08-24 收录
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Crystal Structure of Human cystathionine beta-synthase variant R336C Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE Authors: Conter, C, Martinez-Cruz, L.A, Fernandez-Rodriguez, C. Deposit date: 2024-11-26 Release date: 2025-05-14 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (3.65 Å) Cite: The disease-linked R336C mutation in cystathionine beta-synthase disrupts communication with the PLP cofactor, yet maintains the enzyme's overall structural integrity. Febs J., 292, 2025

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2024-11-26
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