Cytokine concentrations in lung homogenates and plasma of WT and Tie2-EPCR mice during experimental melioidosis.
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Pulmonary and plasma cytokine levels 48 hours after intranasal infection with 300 CFU of B. pseudomallei. Wild type (WT) mice are compared with mice overexpressing EPCR (Tie2-EPCR mice). Data are expressed as median (interquartile ranges) of n = 8–9 mice per group per time point. BD below detection limits, IFN-γ interferon-γ, IL interleukin, MCP-1 monocyte-chemoattractant protein-1, TNF-α tumor necrosis factor-α. *P<0.05, **P<0.01 and ***P<0.001 for WT versus Tie2-EPCR mice (Mann-Whitney U test).
创建时间：
2015-12-02
