Peak allelic associations within genomic regions of sarcoidosis ancestry linkage with Scadding stage IV disease.

Abbreviations: fCEU: frequency of modeled allele in HapMap Northern and Western European ancestry population; fAFR: frequency of modeled allele in HapMap Yoruban African ancestry population; fAFF: frequency of modeled allele in sarcoidosis-affected individuals; fUNF: frequency of modeled allele in unaffected individuals; OR: odds ratio; 95%CI: 95% confidence interval; P: p-value; MIX: MIXSCORE test.1Minor allele in African Americans is bolded; modeled by generalized estimating equations adjusting for percent global West African ancestry and sex.2Accuracy of imputation was assessed for SNPs with p-values −5 in a sub-sample; agreements overall and by genotype are reported in Table S2. Overall imputation accuracy was 96.0% (rs6547087), 99.2% (rs906233), and 99.3% (rs12919626).3For rs145044562, conditional on rs12919626; for rs1077963, conditional on rs145044562 and rs12919626;4No carriers of the A allele of rs145044562 exist within HapMap or 1000 Genomes Project European populations.