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资源简介：
The Functional Analysis of Granulins and Progranulin
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创建时间：
2016-06-30
相关数据集
Examination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/-
Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathw
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PROTEINS RELATED TO PATHOGENESIS OF DISEASES, VIRAL PROTEINS, CELL DIVISION, ...
Our BAG is composed of seven PIs at six different institutions in Italy and Austria. We focus on different protein targets and address diverse biological contexts by combining...
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Senataxin, the helicase mutated in AOA2 and ALS4, plays a role in autophagy regulation [HTS]
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AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
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Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology [14 months]
GRN haploinsufficiency causes frontotemporal lobar degeneration and results in microglial hyperactivation, lysosomal dysfunction and TDP-43 deposition. To understand the contribution of microglial hyp
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