Gene expression differences between wild-type and ZUP1 knock-out mice in liver infected with MHV-A59

To investigate the transcriptome differences between wild-type and ZUP1 knock-out mice in liver when they were infected with MHV, we employed MHV-A59, a hepatic and neuronal tropic murine coronavirus, to infect wild-type and Zup1 knockout mice and colleted liver tissues after MHV infection to perform RNA- sequencing. We then performed gene expression profiling analysis using data obtained from RNA-seq of wild-type and Zup1 knockout mice infected with MHV-A59 for 48 hours.