Neutrophil degranulation genes mark severe disease in infants with respiratory syncytial virus infection_Thys et al.

Whole genome transcriptome was analysed early on the disease course in blood samples from otherwise healthy children <2 years of age, who were either hospitalized (n = 110) or evaluated as outpatients (n = 37) due to RSV infection. Age-matched non-RSV-infected healthy children (n = 51) were analysed in parallel.

在疾病病程早期，对2岁以下健康儿童血液样本的全基因组转录组进行了分析。这些儿童因呼吸道合胞病毒（RSV）感染而住院（n = 110）或作为门诊病人接受评估（n = 37）。同时，对年龄匹配且未感染RSV的健康儿童（n = 51）进行了并行分析。