Text S1 - Systems Biology of Coagulation Initiation: Kinetics of Thrombin Generation in Resting and Activated Human Blood

A complete description of the ODEs for all 76 species in the assembled reaction network, along with the definition of every reaction rate. Essentially all of the model parameters (rate constants and initial conditions) are known or estimated from literature (Table 1). The use of η clarifies changes from the original Hockin-Mann rate constants that are justified by more recent literature measurements (See Table 1 footnotes). Only, the rate of XIIa leakage was estimated (i.e. fitted) based on the difference between simulation and experiment at 0 added T.
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