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Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist AZ10606120

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist AZ10606120 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-({2-[(2-hydroxyethyl)amino]ethyl}amino)quinolin-5-yl]-2-[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]acetamide, ... Authors: Karasawa, A, Kawate, T. Deposit date: 2016-11-29 Release date: 2017-01-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.501 Å) Cite: Structural basis for subtype-specific inhibition of the P2X7 receptor. Elife, 5, 2016
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2016-11-29
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