Supplementary Materials, Source Data, and Analysis Code for "Multi-Omics Characterization of a Musculin-Marked Stromal State in Gastric Cancer with Exploratory Evaluation of Jiedu Sanjie Formula-Associated Compounds"

This record contains supplementary materials, processed source data,and analysis code supporting the manuscript “Multi-OmicsCharacterization of a Musculin-Marked Stromal State in Gastric Cancerwith Exploratory Evaluation of Jiedu Sanjie Formula-AssociatedCompounds.” The deposited materials support the reported candidateprioritization, multi-cohort stromal analyses, single-cell and spatialcontextualization, proteomic contextualization, and exploratorycompound-perturbation analyses. Original third-party raw datasets arenot redistributed and remain available from their respective publicrepositories. The study identifies musculin (MSC) as a reproducible marker of aCAF/ECM-rich gastric-cancer stromal state. The deposited materials donot establish MSC as a causal stromal regulator, a direct regulator ofSMAD3, or a validated pharmacological target of Jiedu Sanjie Formulaor its associated compounds.