The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD02490.
Peptibody was treated with six proteolytic enzymes (trypsin, chymotrypsin, Asp-N, Glu-C, Lys-C and Lys-N) and digested into amenable peptide fragments for LC-MS analysis. The mass spectrometer used wa
Host directed therapies against HIV-1 are thought to be critical for long term containment of the HIV-1 pandemic but remain elusive. Since HIV-1 infects and manipulates important effectors of both the
To elucidate more details of the interaction between the PM (plasma membrane) H+ ATPase and 14-3-3 and to identify novel interaction partners of this multi-protein complex we developed a strategy for