Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE176001
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资源简介：
To identify genes regulating the jamming transition in healthy distal airway epithelia compared to the dysregulated state in idiopathic pulmonary fibrosis epithelia (IPF) we analyzed RNA from three (3) healthy and four (4) IPF patient cells grown at air-liquid-interface (ALI). This bulk analysis of 3 timepointes (days 4, 8, and 14 of ALI) spanning the jamming transition revealed an enrichment for ERBB- and YAP-related genes. Illumina TruSeq library prep was performed on 500 ng from each sample (1 per donor, per timepoint) ran on the NovaSEQ 6000 with 80 million reads per sample. ***Raw data disclaimer: Unable to provide raw sequencing files due to conflict with privacy protection for human subjects.***
创建时间：
2021-07-01
