Crystal structure of JAK2 JH1 in complex with gandotinib
收藏Protein Data Bank Japan2026-03-04 更新2026-04-19 收录
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Crystal structure of JAK2 JH1 in complex with gandotinib Descriptor: 3-[(4-chloranyl-2-fluoranyl-phenyl)methyl]-2-methyl-~{N}-(5-methyl-1~{H}-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine, Tyrosine-protein kinase JAK2 Authors: Miao, Y, Haikarainen, T. Deposit date: 2022-11-10 Release date: 2023-11-22 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Functional and Structural Characterization of Clinical-Stage Janus Kinase 2 Inhibitors Identifies Determinants for Drug Selectivity. J.Med.Chem., 67, 2024
创建时间：
2022-11-10
