Parameters in the cost-effectiveness decision model for severe febrile illness.

RR = risk ratio; Asmp = Assumption; SSA-Sub Saharan and Southern Africa, SEA-South and South-East Asia;
1Rates of access reported in Gomes et al. [2];
2Parameter values varied by 50% above and below the base case value;
3Parameter values varied by 50% below the base case value only, to reflect lower treatment failure rates in Gomes et al. [2];
495% confidence interval reported in Gomes et al. [2];
5Parameter values varied between estimates reported in the two sources;
6Artemether is used alongside quinine in SEA, hence the cost of first-line parenteral antimalarial treatment in this region was assumed to be an average of the cost of quinine treatment and artemether treatment [10];
7National policies for treatment of uncomplicated falciparum malaria vary by country, Average costs were calculated for each region based on region-wide antimalarial drug policy as reported in the 2008 WMR [10];
8Region-specific life tables were used to estimate life expectancy conditional on survival. Japanese life tables were used within a sensitivity analysis.